研究発表、招待講演等一覧   公開件数:50件

No. 発表題名 発表会議名 発表年月日
1 Nterm-phosphatase of soluble epoxide hydrolase (sEH) in the regulation of vascular endothelial inflammation
60th International Society of Thrombosis and Haemostasis
2017/07/12
2 HABP2 (PHBP/FSAP) is the major plasma protease that promote extracellular histone degradation
60th International Society of Thrombosis and Haemostasis
2017/07/12
3 細胞外ヒストンの分解に関与する血漿プロテアーゼHABP2の制御物質の探索
第37回日本血栓止血学会
2017/06/10
4 血管内皮炎症制御における可溶性エポキシドハイドロラーゼN末端phosphataseの機能の解析
日本血栓止血学会
2017/06/10
5 Pharmacological rationale of the action of SMTP, a novel anti-inflammatory thrombolytic for ischemic stroke
10th World Stroke Congress
2016/10/28
6 The first-in-human phase I study of TMS-007, a member of the anti-inflammatory small-molecule thrombolytic SMTP
10th World Stroke Congress
2016/10/28
7 Evaluation of the in vivo action of SMTP-7, a novel small-molecule anti-inflammatory thrombolytic for ischemic stroke
International Congress on Fibrinolysis & Proteolysis
2016/10
8 Nonclinical development and the first-in-human phase I study of TMS-007, a member of the anti-inflammatory small-molecule thrombolytic SMTP
International Society for Fibrinolysis & Proteolysis
2016/10
9 サル心原性脳梗塞モデルにおける抗炎症性血栓溶解薬SMTP-7およびt-PAの作用機序の相違
第38回日本血栓止血学会
2016/06
10 研究概要発表
日中女性科学者シンポジウム
2016/04/06
11 SMTP-7, a profibrinolytic and anti-inflammatory small molecule, in the treatment of embolic stroke in comparison to t-PA.
5th International Conference on Neurology & Epidemiology
2015/11
12 Soluble epoxide hydrolase as an anti-inflammatory target of the thrombolytic stroke drug SMTP
第37回日本血栓止血学会
2015/06
13 Evaluation of the therapeutic effect of novel stroke drug SMTP-7 on embolic stroke in monkeys.
59th International Society of Thrombosis and Haemostasis
2015/06/16
14 Non clinical and clinical development of TMS-007, a member of the anti-inflammatory small-molecule thrombolytic
59th International Society of Thrombosis and Haemostasis
2015/06/16
15 新規脳梗塞治療薬SMTPの非臨床および臨床開発
日本農芸化学会2015
2015/03/27
16 新規脳梗塞治療薬SMTPの抗炎症作用機序の解析
日本農芸化学会2015
2015/03/27
17 Suppression of cancer malignancy via the inhibition of
tumor-associated macrophage activation
Symposium of international academic exchange
2014/09/22
18 Mechanism of the action of SMTP-7, a novel small-molecule modulator of plasminogen activation, that is under development as a drug for stroke treatment
22nd International Society for Fibrinolysis & Proteolysis
2014/07
19 A novel, small molecule-mediated strategy to enhance ADAMTS13 activity.
22nd International Society for Fibrinolysis & Proteolysis
2014/07
20 ADAMTS-13の活性を促進する化合物の探索
第36回日本血栓止血学会
2014/05
21 Soluble epoxide hydrolase as an anti-inflammatory target of the thrombolytic stroke drug candidate SMTP-7.
56th Annual Meeting, The American Society of Hematology
2013/12/16
22 SMTP-7, a novel thrombolytic with an anti-inflammatory potential, improves primate thrombotic stroke with reduced hemorrhage risk: a role of soluble epoxide hydrolase inhibition
58th International Society on Thrombosis and Haemostasis
2013/06/30
23 霊長類モデルにおける SMTP-7 の脳梗塞改善作用
日本農芸化学会2013
2013/03/25
24 可溶性エポキシドハイドロラーゼ阻害活性をもつ新規SMTP同族体の作用解析
日本農芸化学会2013
2013/03/25
25 SMTP-7による抗炎症作用を介した脳梗塞改善作用機序の解明
日本農芸化学会2013
2013/03/25
26 pre-SMTPを用いたSMTP同属体の合成と活性評価
日本農芸化学会2013
2013/03/25
27 SMTP-7, a novel small-molecule thrombolytic, inhibits soluble epoxide hydrolase: mechanism of the anti-inflammatory action
International Stroke Conference 2013
2013/02
28 SMTP-7, a novel thrombolytic with an anti-inflammatory potential, improves thrombotic stroke with little bleeding risk
第35回日本血栓止血学会
2012/06
29 脳梗塞治療効果を有する化合物SMTPの薬理作用発現の機序の解明
第34回日本血栓止血学会
2012/06
30 SMTP-7の霊長類血栓性脳梗塞モデルに対する効果
第37回日本脳卒中学会総会
2012/04/27
31 脳梗塞治療効果を有する化合物SMTPの薬理作用発現の機序の解明
第37回日本脳卒中学会総会
2012/04/27
32 プラスミノーゲンモジュレーターSMTP生合成の鍵となる新規前駆体pre-SMTPの発見
日本農芸化学会2012
2012/03/24
33 微生物由来低分子化合物SMTP-7による脳梗塞治療効果発現の分子基盤解析
日本農芸化学会2012
2012/03/23
34 Identification of molecular target of SMTP, a candidate therapeutic compound for stroke, and evaluation of molecular mechanism
57th International Society of Thrombosis and Haemostasis
2011/06/16
35 プラスミノーゲンモジュレータSMTP-7の作用機序の解析
日本農芸化学会2011
2011/03/27
36 血栓溶解活性を有する化合物SMTPsの脳梗塞治療作用の検討
日本農芸化学会2011
2011/03/26
37 新規脳梗塞治療薬SMTPsのsoluble epoxyde hydrolase阻害活性の評価
日本農芸化学会2011
2011/03/26
38 Synergistic therapeutic effect of NF-kB and AP-1 function inhibitors on suppression of cell growth against highly aggressive bladder cancer cells.
American Urological Association
2010/05
39 腎癌細胞における有機アニオントランスポーターOAT1の薬剤感受性への寄与
日本泌尿器科学会
2010/04
40 Inhibition of inflammatory cell function by an NF-kappa B inhibitor
Jozef Stefan International Postgraduate School Lecture
2009/11/10
41 腎癌細胞表面のSLCトランスポーターOAT1による抗癌剤の取り込みと低酸素による影響
日本癌学会学術総会
2009/10
42 Inhibition of CARD11/Bcl-10/Malt1 complex-mediated leukotriene production by a specific NF-kappa B inhibitor, (-)-DHMEQ, in basophils. 2nd European Congress of Immunology
2nd European Congress of Immunology
2009/09
43 腎癌細胞表面のSLCトランスポーターOAT1による抗癌剤の取り込みと低酸素による影響
第13回がん分子標的治療学会
2009/06
44 In vitro and in vivo anti-neoplastic activity of the specific NF-κB inhibitor DHMEQ on human multiple myeloma.
2nd International Conference on Lymphoma, Leukemia and Multiple Myeloma
2009/05
45 Management of malignancies by reduction of systemic immune reactions.
Multidisciplinary Conference
2008/10
46 Inhibition of leukotriene production by (-)-DHMEQ in rat basophilic leukemia cells
World Congress on Advances in Oncology and 10th International Symposium on Molecular Medicine and Cancer Chemoprevention Symposium
2007/10
47 Sensitization of B-NHL resistant tumor cells overexpressing Bcl-xL to TRAIL-induced apoptosis by the novel proteasome inhibitor Salinosporamide A (NPI-0052)
American Association of Cancer Research,
2007/04
48 Rituximab-mediated sensitization of resistant B-NHL cell lines to NPI-0052 (proteasome inhibitor)-induced apoptosis: pivotal role of PTEN induction and inhibition of Bcl-xL.
American Association of Cancer Research
2007/04
49 Mechanism of chemosensitization of drug-resistant MM cell lines by an IgG3-avidin fusion protein targeting the transferring receptor: inhibition of the Akt pathway and downregulation of XIAP and Bcl-xl expressions.
American association of cancer research
2007/04/16
50 Rituximab sensitizes resistant B-NHL cell lines to the proteasome inhibitor NPI-0052-induced apoptosis American Association of Cancer Research,
American Association of Cancer Research,
2006/04